Reactive species
Human;Mouse
Protein name
Mitochondrial inner membrane protease subunit 1 (EC 3.4.21.-) (IMP1-like protein)
Immunogen
Synthesized peptide derived from human protein . at AA range: 70-150
Specificity
IMP1L Monoclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The mitochondrial inner membrane peptidase (IMP) complex generates mature, active proteins in the mitochondrial intermembrane space by proteolytically removing the mitochondrial targeting presequence of nuclear-encoded proteins. IMP1 and IMP2 (IMMP2L; MIM 605977) are the catalytic subunits of the IMP complex (Burri et al., 2005 [PubMed 15814844]).[supplied by OMIM, Sep 2008],
Function
function:Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.,similarity:Belongs to the peptidase S26 family. IMP1 subfamily.,subunit:Heterodimer of 2 subunits, IMMPL1 and IMMPL2.,
