Reactive species
Human;Rat;Mouse;
Gene Name
GPATCH8 GPATC8 KIAA0553
Protein name
G patch domain-containing protein 8
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
GPTC8 Monoclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene contains an RNA-processing domain, a zinc finger domain, a lysine-rich region and a serine-rich region. A mutation in the serine-rich region of the protein is thought to be associated with hyperuricemia (PMID: 21594610). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2015],
Function
PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,
