Reactive species
Human;Mouse;Rat
Protein name
cGMP-dependent 3',5'-cyclic phosphodiesterase (EC 3.1.4.17) (Cyclic GMP-stimulated phosphodiesterase) (CGS-PDE) (cGSPDE)
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
PDE2A Monoclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Background
alternative products:Additional isoforms seem to exist. Experimental confirmation may be lacking for some isoforms,catalytic activity:Nucleoside 3',5'-cyclic phosphate + H(2)O = nucleoside 5'-phosphate.,function:Hydrolyzes both cyclic AMP (cAMP) and cyclic GMP (cGMP).,similarity:Belongs to the cyclic nucleotide phosphodiesterase family.,similarity:Contains 2 GAF domains.,subunit:Homodimer.,tissue specificity:Expressed in brain and to a lesser extent in heart, placenta, lung, skeletal muscle, kidney and pancreas.,
Function
alternative products:Additional isoforms seem to exist. Experimental confirmation may be lacking for some isoforms,catalytic activity:Nucleoside 3',5'-cyclic phosphate + H(2)O = nucleoside 5'-phosphate.,function:Hydrolyzes both cyclic AMP (cAMP) and cyclic GMP (cGMP).,similarity:Belongs to the cyclic nucleotide phosphodiesterase family.,similarity:Contains 2 GAF domains.,subunit:Homodimer.,tissue specificity:Expressed in brain and to a lesser extent in heart, placenta, lung, skeletal muscle, kidney and pancreas.,