Reactive species
Human;Mouse
Protein name
Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R)
Immunogen
Synthesized peptide derived from human protein . at AA range: 350-430
Specificity
EP15R Monoclonal Antibody detects endogenous levels of protein.
Constitute
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis.,PTM:Phosphorylated on tyrosine residues by EGFR.,similarity:Contains 1 EF-hand domain.,similarity:Contains 3 EH domains.,subcellular location:Localized to plasma membrane coated pits.,subunit:Interacts with EPS15, AGFG1/HRB and AGFG2/HRBL. Associates with the clathrin-associated adapter protein complex 2 (AP-2).,
Function
function:Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis.,PTM:Phosphorylated on tyrosine residues by EGFR.,similarity:Contains 1 EF-hand domain.,similarity:Contains 3 EH domains.,subcellular location:Localized to plasma membrane coated pits.,subunit:Interacts with EPS15, AGFG1/HRB and AGFG2/HRBL. Associates with the clathrin-associated adapter protein complex 2 (AP-2).,
