Reactive species
Human;Rat;Mouse;
Protein name
Sideroflexin-4
Immunogen
The antiserum was produced against synthesized peptide derived from human SFXN4. AA range:1-50
Specificity
Sideroflexin-4 Monoclonal Antibody detects endogenous levels of Sideroflexin-4 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
SFXN4; BCRM1; Sideroflexin-4; Breast cancer resistance marker 1
Background
This gene encodes a member of the sideroflexin family. The encoded protein is a transmembrane protein of the inner mitochondrial membrane, and is required for mitochondrial respiratory homeostasis and erythropoiesis. Mutations in this gene are associated with mitochondriopathy and macrocytic anemia. Alternatively spliced transcript variants have been found in this gene. [provided by RefSeq, Jan 2014],
Function
function:Potential iron transporter.,similarity:Belongs to the sideroflexin family.,
