Reactive species
Human;Rat;Mouse;
Protein name
Plasma serine protease inhibitor
Immunogen
The antiserum was produced against synthesized peptide derived from human Serpin A5. AA range:260-309
Specificity
PAI-3 Monoclonal Antibody detects endogenous levels of PAI-3 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
WB: 1/500 - 1/2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
SERPINA5; PCI; PLANH3; Plasma serine protease inhibitor; Acrosomal serine protease inhibitor; Plasminogen activator inhibitor 3; PAI-3; PAI3; Protein C inhibitor; PCI; Serpin A5
Background
The protein encoded by this gene is a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. This gene is one in a cluster of serpin genes located on the q arm of chromosome 14. This family member is a glycoprotein that can inhibit several serine proteases, including protein C and various plasminogen activators and kallikreins, and it thus plays diverse roles in hemostasis and thrombosis in multiple organs. [provided by RefSeq, Aug 2012],
Function
function:Inhibits activated protein C as well as plasminogen activators.,similarity:Belongs to the serpin family.,tissue specificity:Expressed by the liver and secreted in plasma.,
