Reactive species
Human;Rat;Mouse;
Protein name
Polyadenylate-binding protein 3
Immunogen
The antiserum was produced against synthesized peptide derived from human PABPC3. AA range:352-401
Specificity
PABP3 Monoclonal Antibody detects endogenous levels of PABP3 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
WB: 1/500 - 1/2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
PABPC3; PABP3; PABPL3; Polyadenylate-binding protein 3; PABP-3; Poly(A)-binding protein 3; Testis-specific poly(A)-binding protein
Background
Messenger RNA stability and translation initiation are extensively under the control of poly(A)-binding proteins (MABP). See MABPC1 (MIM 604679) for background information.[supplied by OMIM, Jul 2002],
Function
function:Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Binds poly(A) with a slightly lower affinity as compared to MABPC1.,similarity:Belongs to the polyadenylate-binding protein type-1 family.,similarity:Contains 1 MABC domain.,similarity:Contains 4 RRM (RNA recognition motif) domains.,tissue specificity:Testis specific.,
