Reactive species
Human;Mouse;Rat
Protein name
Protein NDRG4
Immunogen
The antiserum was produced against synthesized peptide derived from human NDRG4. AA range:187-236
Specificity
NDRG4 Monoclonal Antibody detects endogenous levels of NDRG4 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
WB: 1/500 - 1/2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
NDRG4; BDM1; KIAA1180; Protein NDRG4; Brain development-related molecule 1; N-myc downstream-regulated gene 4 protein; Vascular smooth muscle cell-associated protein 8; SMAP-8
Background
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that is required for cell cycle progression and survival in primary astrocytes and may be involved in the regulation of mitogenic signalling in vascular smooth muscles cells. Alternative splicing results in multiple transcripts encoding different isoforms.[provided by RefSeq, Jun 2011],
Function
function:May play a role in the early postnatal development and function of neuronal cells.,similarity:Belongs to the NDRG family.,tissue specificity:Expressed only in brain and heart. Isoform 1 and isoform 2 are only expressed in brain. Isoform 3 is expressed in both heart and brain.,
