Reactive species
Human;Rat;Mouse;
Protein name
Carboxypeptidase N subunit 2
Immunogen
Synthesized peptide derived from the C-terminal region of human CPN reg.
Specificity
CPN reg Monoclonal Antibody detects endogenous levels of CPN reg protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
Western Blot: 1/500 - 1/2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
CPN2; ACBP; Carboxypeptidase N subunit 2; Carboxypeptidase N 83 kDa chain; Carboxypeptidase N large subunit; Carboxypeptidase N polypeptide 2; Carboxypeptidase N regulatory subunit
Background
function:The 83 kDa subunit binds and stabilizes the catalytic subunit at 37 degrees Celsius and keeps it in circulation. Under some circumstances it may be an allosteric modifier of the catalytic subunit.,PTM:Whether or not any Cys residues participate in intrachain bonds is unknown, but they do not form interchain disulfide bonds with the 50 kDa catalytic subunit.,similarity:Contains 13 LRR (leucine-rich) repeats.,subunit:Tetramer of two catalytic chains and two glycosylated inactive chains.,
Function
function:The 83 kDa subunit binds and stabilizes the catalytic subunit at 37 degrees Celsius and keeps it in circulation. Under some circumstances it may be an allosteric modifier of the catalytic subunit.,PTM:Whether or not any Cys residues participate in intrachain bonds is unknown, but they do not form interchain disulfide bonds with the 50 kDa catalytic subunit.,similarity:Contains 13 LRR (leucine-rich) repeats.,subunit:Tetramer of two catalytic chains and two glycosylated inactive chains.,