Protein name
Tyrosine 3-monooxygenase
Immunogen
The antiserum was produced against synthesized peptide derived from human Tyrosine Hydroxylase. AA range:5-54
Specificity
TH Monoclonal Antibody detects endogenous levels of TH protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
WB: 1/500 - 1/2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
TH; TYH; Tyrosine 3-monooxygenase; Tyrosine 3-hydroxylase; TH
Background
Tyrosine 3-monooxygenase encoded by TH is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have be associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
