Reactive species
Human;Rat;Mouse;
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 80-160 of human
NDUFS7 (NP_077718.3).
Dilution rate
WB: 1/500 - 1/2000
Purification process
Affinity purification
Stockpile
Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Other name
NDUFS7; CI-20; CI-20KD; MY017; PSST; NADH:ubiquinone oxidoreductase core subunit S7
Background
This gene encodes a protein that is a subunit of one of the complexes that forms the
mitochondrial respiratory chain. This protein is one of over 40 subunits found in complex I,
the nicotinamide adenine dinucleotide (NADH):ubiquinone oxidoreductase. This complex
functions in the transfer of electrons from NADH to the respiratory chain, and ubiquinone is
believed to be the immediate electron acceptor for the enzyme. Mutations in this gene cause
Leigh syndrome due to mitochondrial complex I deficiency, a severe neurological disorder
that results in bilaterally symmetrical necrotic lesions in subcortical brain regions
