Reactive species
Human;Rat
Protein name
Aldehyde oxidase
Immunogen
The antiserum was produced against synthesized peptide derived from human AOX1. AA range:521-570
Specificity
AOX1 Monoclonal Antibody detects endogenous levels of AOX1 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
WB: 1/500 - 1/2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
AOX1; AO; Aldehyde oxidase
Background
Aldehyde oxidase produces hydrogen peroxide and, under certain conditions, can catalyze the formation of superoxide. Aldehyde oxidase is a candidate gene for amyotrophic lateral sclerosis. [provided by RefSeq, Jul 2008],
Function
catalytic activity:An aldehyde + H(2)O + O(2) = a carboxylic acid + H(2)O(2).,caution:Was originally (PubMed:8248161) thought to be a xanthine dehydrogenase.,cofactor:Binds 2 2Fe-2S clusters.,cofactor:FAD.,cofactor:Molybdopterin.,similarity:Belongs to the xanthine dehydrogenase family.,similarity:Contains 1 2Fe-2S ferredoxin-type domain.,similarity:Contains 1 FAD-binding PCMH-type domain.,subunit:Homodimer.,tissue specificity:Abundant in liver, lower levels in lung, skeletal muscle, pancreas. Undetected in heart, brain and kidney.,
