Reactive species
Human;Mouse;Rat
Protein name
Alcohol dehydrogenase [NADP(+)]
Immunogen
Synthesized peptide derived from AKR1A1 . at AA range: 250-330
Specificity
AKR1A1 Monoclonal Antibody detects endogenous levels of AKR1A1 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
Western Blot: 1/500 - 1/2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
AKR1A1; ALDR1; ALR; Alcohol dehydrogenase [NADP(+)]; Aldehyde reductase; Aldo-keto reductase family 1 member A1
Background
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member, also known as aldehyde reductase, is involved in the reduction of biogenic and xenobiotic aldehydes and is present in virtually every tissue. Multiple alternatively spliced transcript variants of this gene exist, all encoding the same protein. [provided by RefSeq, Jan 2011],
Function
catalytic activity:An alcohol + NADP(+) = an aldehyde + NADPH.,function:Catalyzes the NADPH-dependent reduction of a variety of aldehydes to their corresponding alcohols.,similarity:Belongs to the aldo/keto reductase family.,subunit:Monomer.,