Reactive species
Human;Rat;Mouse;
Protein name
Zinc finger protein with KRAB and SCAN domains 4
Immunogen
Synthesized peptide derived from the Internal region of human ZKSCAN4.
Specificity
ZKSCAN4 Monoclonal Antibody detects endogenous levels of ZKSCAN4 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
WB: 1/500 - 1/2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
ZKSCAN4; ZNF307; ZNF427; Zinc finger protein with KRAB and SCAN domains 4; P373c6.1; Zinc finger protein 307; Zinc finger protein 427
Background
function:May be involved in the transcriptional activation of MDM2 and EP300 genes.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 1 KRAB domain.,similarity:Contains 1 SCAN box domain.,similarity:Contains 7 C2H2-type zinc fingers.,tissue specificity:Expressed in adult heart, brain, placenta, lung and kidney, but not in adult liver and skeletal muscle. In 17-day old embryo, detected in liver, skeletal muscle, brain, heart and small intestine.,
Function
function:May be involved in the transcriptional activation of MDM2 and EP300 genes.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 1 KRAB domain.,similarity:Contains 1 SCAN box domain.,similarity:Contains 7 C2H2-type zinc fingers.,tissue specificity:Expressed in adult heart, brain, placenta, lung and kidney, but not in adult liver and skeletal muscle. In 17-day old embryo, detected in liver, skeletal muscle, brain, heart and small intestine.,
