Reactive species
Human;Mouse
Protein name
PHD finger protein 3
Immunogen
The antiserum was produced against synthesized peptide derived from human PHF3. AA range:1990-2039
Specificity
PHF3 Monoclonal Antibody detects endogenous levels of PHF3 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
WB: 1/500 - 1/2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
PHF3; KIAA0244; PHD finger protein 3
Background
This gene encodes a member of a PHD finger-containing gene family. This gene may function as a transcription factor and may be involved in glioblastomas development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014],
Function
PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 PHD-type zinc finger.,similarity:Contains 1 TFIIS central domain.,tissue specificity:Ubiquitous. Expression is significantly reduced or lost in glioblastomas, glioblastoma cell lines, anaplastic astrocytomas, and astrocytomas.,
