Reactive species
Human;Mouse
Protein name
Helix-loop-helix protein 1
Immunogen
The antiserum was produced against synthesized peptide derived from human HEN1/2. AA range:41-90
Specificity
HEN1/2 Monoclonal Antibody detects endogenous levels of HEN1/2 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
WB: 1/500 - 1/2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
NHLH1; BHLHA35; HEN1; Helix-loop-helix protein 1; HEN-1; Class A basic helix-loop-helix protein 35; bHLHa35; Nescient helix loop helix 1; NSCL-1; NHLH2; BHLHA34; HEN2; KIAA0490; Helix-loop-helix protein 2; HEN-2; Class A basic helix-loop-he
Background
The helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080), LYL1 (MIM 151440), E2A (MIM 147141), and SCL (MIM 187040).[supplied by OMIM, Nov 2002],
Function
function:May serve as DNA-binding protein and may be involved in the control of cell-type determination, possibly within the developing nervous system.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein.,
