Reactive species
Human;Rat;Mouse;
Protein name
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2
Immunogen
The antiserum was produced against synthesized peptide derived from human BNIP2. AA range:265-314
Specificity
BNIP-2 Monoclonal Antibody detects endogenous levels of BNIP-2 protein.
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Monoclonal, Mouse,IgG
Dilution rate
Western Blot: 1/500 - 1/2000
Purification process
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
Other name
BNIP2; NIP2; BCL2/adenovirus E1B 19 kDa protein-interacting protein 2
Background
This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
Function
function:Implicated in the suppression of cell death. Interacts with the BCL-2 and adenovirus E1B 19 kDa proteins.,similarity:Contains 1 CRAL-TRIO domain.,subcellular location:Localizes to the nuclear envelope region and to other cytoplasmic structures.,