Reactive species
Human,Mouse,Rat
Protein name
Carnitine O-acetyltransferase (Carnitine acetylase) (Carnitine acetyltransferase) (CAT) (CrAT)
Immunogen
Synthesized peptide derived from human CRAT
Specificity
This antibody detects endogenous levels of CRAT at Human, Mouse,Rat
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Stockpile
-15°C to -25°C/1 year(Do not lower than -25°C)
Function
Catalyzes the reversible transfer of acyl groups from carnitine to coenzyme A (CoA) and regulates the acyl-CoA/CoA ratio. Also plays a crucial role in the transport of fatty acids for beta-oxidation . Responsible for the synthesis of short- and branched-chain acylcarnitines . Active towards some branched-chain amino acid oxidation pathway (BCAAO) intermediates . Trans-2-enoyl-CoAs and 2-methylacyl-CoAs are poor substrates .
