Reactive species
Human,Mouse
Gene Name
COA3 CCDC56 HSPC009
Protein name
Cytochrome C oxidase assembly factor 3 homolog, mitochondrial (Coiled-coil domain-containing protein 56)
Immunogen
Synthesized peptide derived from human CCDC56
Specificity
This antibody detects endogenous levels of CCDC56 at Human, Mouse
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Stockpile
-15°C to -25°C/1 year(Do not lower than -25°C)
Function
Core component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly.
