Reactive species
Human,Mouse,Rat
Protein name
Homeobox protein CDX-1 (Caudal-type homeobox protein 1)
Immunogen
Synthesized peptide derived from human CDX1
Specificity
This antibody detects endogenous levels of CDX1 at Human, Mouse,Rat
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Stockpile
-15°C to -25°C/1 year(Do not lower than -25°C)
Function
Plays a role in transcriptional regulation . Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells . Binds to the PRKD1 promoter in colorectal cancer (CRC) cells . Could play a role in the terminal differentiation of the intestine. Binds preferentially to methylated DNA .
