Reactive species
Human;Mouse
Gene Name
MUC20 KIAA1359 UNQ2782/PRO7170
Protein name
Mucin-20 (MUC-20)
Immunogen
Synthesized peptide derived from human MUC20
Specificity
This antibody detects endogenous levels of MUC20 at Human, Mouse
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Rabbit Polyclonal antibody
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Stockpile
-15°C to -25°C/1 year(Do not lower than -25°C)
Function
May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression.
