Reactive species
Human;Mouse
Antibody type
Polyclonal Antibody
Gene Name
THEMIS C6orf190 C6orf207
Protein name
Protein THEMIS (Thymocyte-expressed molecule involved in selection)
Immunogen
Synthesized peptide derived from human TSEPA
Specificity
This antibody detects endogenous levels of TSEPA at Human, Mouse
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Stockpile
-15°C to -25°C/1 year(Do not lower than -25°C)
Function
Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk.
