Reactive species
Human;Mouse
Antibody type
Polyclonal Antibody
Gene Name
CCPG1 CCP8 CPR8 KIAA1254
Protein name
Cell cycle progression protein 1 (Cell cycle progression restoration protein 8)
Immunogen
Synthesized peptide derived from human CCPG1
Specificity
This antibody detects endogenous levels of CCPG1 at Human, Mouse
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Stockpile
-15°C to -25°C/1 year(Do not lower than -25°C)
Function
Acts as an assembly platform for Rho protein signaling complexes. Limits guanine nucleotide exchange activity of MCF2L toward RHOA, which results in an inhibition of both its transcriptional activation ability and its transforming activity. Does not inhibit activity of MCF2L toward CDC42, or activity of MCF2 toward either RHOA or CDC42 (By similarity). May be involved in cell cycle regulation.
