Reactive species
Human;Mouse
Antibody type
Polyclonal Antibody
Protein name
Ceramide kinase (hCERK) (EC 2.7.1.138) (Acylsphingosine kinase) (Lipid kinase 4) (LK4)
Immunogen
Synthesized peptide derived from human CERK
Specificity
This antibody detects endogenous levels of CERK at Human, Mouse
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Stockpile
-15°C to -25°C/1 year(Do not lower than -25°C)
Function
Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate . Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines . Shows a greater preference for D-erythro isomer of ceramides . Binds phosphoinositides .
