Reactive species
Human;Mouse;Rat
Antibody type
Polyclonal Antibody
Protein name
Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
Immunogen
Synthesized peptide derived from human VAMP2
Specificity
This antibody detects endogenous levels of VAMP2 at Human, Mouse,Rat
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Stockpile
-15°C to -25°C/1 year(Do not lower than -25°C)
Function
Involved in the targeting and/or fusion of transport vesicles to their target membrane (By similarity). Major SNARE protein of synaptic vesicles which mediates fusion of synaptic vesicles to release neurotransmitters. Essential for fast vesicular exocytosis and activity-dependent neurotransmitter release as well as fast endocytosis that mediates rapid reuse of synaptic vesicles (By similarity) . Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1.
