Applications
IHC;WB;IF;ELISA
Antibody type
Monoclonal antibodies
Immunogen
Synthesized peptide derived from human Galectin 3 AA range: 150-250
Specificity
The antibody can specifically recognize human Galectin 3 protein. In western blotting of Hela, A431 and MCF7 cell lysates, the antibody can label a 30 kDa band corresponding to Galectin 3, while there
Constitute
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
Mouse, Monoclonal/IgG2b, kappa
Dilution rate
IHC 1:200-1000. WB 1:500-2000. IF 1:100-500. ELISA 1:1000-5000
Purification process
Protein G
Stockpile
-15°C to -25°C/1 year(Do not lower than -25°C)
Other name
90K；90K MAC 2 BP；Basement membrane autoantigen p105；BTBD17B；Galectin 3 binding protein；Galectin-3-binding protein；L3 antigen；Lectin galactoside binding soluble 3 binding protein；Lectin galactoside-binding soluble 3-binding protein；LG3BP_HUMAN；LGALS3BP；M2BP；Mac 2 binding protein；Mac 2 BP；Mac-2 BP；Mac-2-binding protein；Mac2 BP；MAC2BP；Serum protein 90K；TANGO10B；Transport and golgi organization 10 homolog B；Tumor associated antigen 90K；Tumor-associated antigen 90K
Background
Galectin-3 is a member of the β-galactose binding lectin family with a molecular weight of 30 kDa which is a chimeric structure consisting of a β-galactoside binding protein and a laminin. The main role of Galectin-3 on the cell surface is related to the adhesion between similar cells. It is expressed in a variety of organs and tissues, including neutrophils and vascular endothelial cells, but it is obviously absent in normal hepatocytes. Galectin-3 can downregulate the expression of some cancers and breast cancer associated proteins, and promote tumor metastasis. It can be used as a reference index for the degree of tumor deterioration.
Function
function:Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis.,online information:Galectin-3,simi
