Reactive species
Human;Mouse;Rat
Antibody type
Polyclonal Antibody
Gene Name
BSN KIAA0434 ZNF231
Protein name
Protein bassoon (Zinc finger protein 231)
Immunogen
Synthesized peptide derived from human Bassoon/BSN
Specificity
This antibody detects endogenous levels of Bassoon/BSNat Human, Mouse,Rat
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02%sodiumazide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit antiserumby
affinity-chromatography using epitope-specific immunogen.
Stockpile
-15°C to -25°C/1 year(Do not lower than -25°C)
Function
Scaffold protein of the presynaptic cytomatrix at the active zone (CAZ) whichisthe place in the synapse where neurotransmitter is released . After synthesis,participates in the formation of Golgi-derived membranous organellestermedPiccolo-Bassoon transport vesicles (PTVs) that are transported alongaxonstosites of nascent synaptic contacts . At the presynaptic active zone, regulatesthespatial organization of synaptic vesicle cluster, the protein complexesthat
execute membrane fusion and compensatory endocytosis (By similarity). Functions also in processes other than assembly such as the regulationof
specific presynaptic protein ubiquitination by interacting with SIAH1or theregulation of presynaptic autophagy by associating with ATG5 (By similarity).Mediates also synapse to nucleus communication leading to reconfigurationofgene expression by associating with the transcrip
