Reactive species
Human;Mouse
Antibody type
Polyclonal Antibody
Gene Name
NOTUM OK/SW-CL.30
Protein name
Protein notum homolog (EC 3.-.-.-)
Immunogen
Synthesized peptide derived from human NOTUM
Specificity
This antibody detects endogenous levels of NOTUM at Human, Mouse
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Stockpile
-15°C to -25°C/1 year(Do not lower than -25°C)
Function
Carboxylesterase that acts as a key negative regulator of the Wnt signaling pathway by specifically mediating depalmitoleoylation of WNT proteins. Serine palmitoleoylation of WNT proteins is required for efficient binding to frizzled receptors .
