Reactive species
Human; Mouse; Rat
Applications
IHC;WB;IF;ELISA
Antibody type
Monoclonal antibodies
Protein name
Allograft inflammatory factor 1 (AIF-1) (Ionized calcium-binding adapter molecule 1) (Protein G1)
Immunogen
Synthesized peptide derived from part region of human protein AA range: 50-147
Specificity
This antibody detects endogenous levels of AIF1 protein.
Constitute
PBS, pH7.4, 50% glycerol, 0.05% Proclin 300
Source
Monoclonal, Mouse IgG1, Kappa
Dilution rate
IHC 1:200-1000. WB 1:500-2000. IF 1:100-500. ELISA 1:1000-5000
Purification process
Protein G
Stockpile
-15°C to -25°C/1 year(Do not lower than -25°C)
Other name
AIF 1;AIF-1;Aif1;AIF1 protein;AIF1_HUMAN;Allograft inflammatory factor 1;Allograft inflammatory factor 1 splice variant G;allograft inflammatory factor-1 splice variant Hara-1;balloon angioplasty responsive transcription;BART 1;G1;G1 putative splice variant of allograft inflamatory factor 1;IBA 1;IBA1;interferon gamma responsive transcript;Interferon responsive transcript 1;interferon responsive transcript factor 1;Ionized calcium binding adapter molecule 1;Ionized calcium-binding adapter molecule 1;ionized calcium-binding adapter molecule;IRT 1;IRT1;Microglia response factor;MRF1;Protein g1;
Background
This gene encodes a protein that binds actin and calcium. This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T-lymphocytes. Polymorphisms in this gene may be associated with systemic sclerosis. Alternative splicing results in multiple transcript variants, but the full-length and coding nature of some of these variants is not certain. [provided by RefSeq, Jan 2016],
Function
function:May play a role in macrophage activation and function.,PTM:Phosphorylated on serine residues.,similarity:Contains 2 EF-hand domains.,
