Reactive species
Human;Mouse;Rat
Antibody type
Polyclonal Antibody
Protein name
Axin-2 (Axin-like protein) (Axil) (Axis inhibition protein 2) (Conductin)
Immunogen
Synthesized peptide derived from human AXIN2
Specificity
This antibody detects endogenous levels of AXIN2 at Human, Mouse,Rat
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Stockpile
-15°C to -25°C/1 year(Do not lower than -25°C)
Function
Inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. Probably facilitate the phosphorylation of beta-catenin and APC by GSK3B.