Reactive species
Human;Mouse;Rat
Antibody type
Polyclonal Antibody
Gene Name
SLC40A1 FPN1 IREG1 SLC11A3 MSTP079
Protein name
Solute carrier family 40 member 1 (Ferroportin-1) (Iron-regulated transporter 1)
Immunogen
Synthesized peptide derived from human SLC40A1. AA range 1-100
Specificity
This antibody detects endogenous levels of SLC40A1 at Human, Mouse,Rat
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Stockpile
-15°C to -25°C/1 year(Do not lower than -25°C)
Function
Major iron transporter that plays a key role in balancing cellular and systemic iron levels . Transports iron from intestinal, splenic, and hepatic cells into the blood to provide iron to other tissues (By similarity). Controls therefore dietary iron uptake, iron recycling by macrophages, and release of iron stores in hepatocytes (By similarity). When iron is in excess, hepcidin/HAMP levels increase resulting in a degradation of ferroportin/SLC40A1 limiting the iron efflux to plasma .
