Reactive species
Human;Mouse
Antibody type
Polyclonal Antibody
Gene Name
WAPAL FOE KIAA0261 WAPL
Protein name
Wings apart-like protein homolog (Friend of EBNA2 protein)
Immunogen
Synthesized peptide derived from human WAPL; WAPAL
Specificity
This antibody detects endogenous levels of WAPL; WAPAL at Human, Mouse
Constitute
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Polyclonal, Rabbit,IgG
Dilution rate
WB 1:500-2000
Purification process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Stockpile
-15°C to -25°C/1 year(Do not lower than -25°C)
Function
Regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin. Involved in both sister chromatid cohesion during interphase and sister-chromatid resolution during early stages of mitosis. Couples DNA replication to sister chromatid cohesion. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair.
