Reactive species
Human,Mouse,Rat
Applications
WB,IHC-P,ICC/IF,IP,FC
Antibody type
Monoclonal antibodies
Dalton（DA）
Calculated MW: 80 kDa; Observed MW: 90 kDa
Immunogen
synthesized peptide derived from human PSD95
Dilution rate
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100
Stockpile
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Other name
DLG4; Disks large homolog 4; PSD95; SAP90; Synapse associated protein 90
Background
Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons.
