Reactive species
Human,Mouse,Rat
Applications
WB,IHC-P,ICC/IF
Antibody type
Monoclonal antibodies
Dalton（DA）
Calculated MW: 54 kDa; Observed MW: 54 kDa
Immunogen
synthesized peptide derived from human PI 3 Kinase p55 gamma
Dilution rate
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/20
Stockpile
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Other name
GRB1; P85A; PI3-kinase p85-alpha subunit; PI3K; PI3K p85-alpha; P55G; PI3-kinase p85-gamma subunit; PI3K p85-gamma
Background
Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1. Highest levels in brain and testis. Lower levels in adipose tissue, kidney, heart, lung and skeletal muscle.
