Reactive species
Human,Mouse,Rat
Applications
WB,IHC-P,ICC/IF,IP
Antibody type
Monoclonal antibodies
Dalton（DA）
Calculated MW: 34 kDa; Observed MW: 34 kDa
Immunogen
synthesized peptide derived from human TRADD
Dilution rate
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/10
Stockpile
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Background
Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.
