Reactive species
Human,Mouse,Rat
Applications
WB,IHC-P,ICC/IF
Antibody type
Polyclonal Antibody
Dalton(DA)
Calculated MW: 17 kDa; Observed MW: 17 kDa
Immunogen
Recombinant protein of human FIS1 (NP_057152.2).
Dilution rate
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Stockpile
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Other name
CGI135; FIS1; hFis1; TTC 11
Background
Promotes the fragmentation of the mitochondrial network and its perinuclear clustering. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission.