Reactive species
Human,Mouse,Rat
Applications
WB,ICC/IF,IP
Antibody type
Monoclonal antibodies
Dalton(DA)
Calculated MW: 139 kDa; Observed MW: 150 kDa
Immunogen
Recombinant protein of human Collagen III
Dilution rate
WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
Stockpile
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Other name
EDS4A; EDSVASC
Background
Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the RhoA pathway by coupling ADGRG1 to GNA13 and possibly GNA12.