Reactive species
Human,Mouse,Rat
Antibody type
Monoclonal antibodies
Dalton(DA)
Calculated MW: 84 kDa; Observed MW:84 kDa
Dilution rate
WB:1/500-1/1000,IHC-P:1/50-1/100
Stockpile
Store at -20°C. Avoid freeze/thaw cycles.
Background
Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion. Membrane clustering requires GTPase activity. It may involve a major rearrangement of the coiled coil domains. Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events. Overexpression induces the formation of mitochondrial networks (in vitro). Has low GTPase activity.