Antibody type
Monoclonal antibodies
Dalton(DA)
Calculated MW: 60 kDa; Observed MW: 65 kDa
Immunogen
synthesized peptide derived from human NF-κB p65
Dilution rate
WB: 1/500-1/1000 IP: 1/50 FC: 1/50
Stockpile
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Other name
NFKB3; RELA; TF65; Transcription factor p65; p65; NFkB
Background
NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA, or RELB (MIM 604758) to form the NFKB complex. The p50 (NFKB1)/p65 (RELA) heterodimer is the most abundant form of NFKB. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008 or NFKBIB, MIM 604495), which inactivate NFKB by trapping it in the cytoplasm.