Reactive species
Human,Mouse,Rat
Applications
WB,IHC-F,IHC-P,ICC/IF
Antibody type
Polyclonal Antibody
Dalton（DA）
Calculated MW: 22 kDa; Observed MW: 17 kDa
Immunogen
A synthesized peptide derived from human GPX4
Dilution rate
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Stockpile
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Other name
Phospholipid hydroperoxide glutathione peroxidase; mitochondrial; PHGPx; EC 1.11.1.12; Glutathione peroxidase 4; GPx-4; GSHPx-4
Background
Protects cells against membrane lipid peroxidation and cell death. Required for normal sperm development and male fertility. Could play a major role in protecting mammals from the toxicity of ingested lipid hydroperoxides. Essential for embryonic development. Protects from radiation and oxidative damage.
