Reactive species
Human,Mouse,Rat
Applications
WB,IHC-P,ICC/IF,IP,FC
Antibody type
Monoclonal antibodies
Gene Name
MAPK8/MAPK9/MAPK10
Dalton（DA）
Calculated MW: 48 kDa; Observed MW: 46,54 kDa
Immunogen
synthesized peptide derived from human Phospho-JNK1/2/3 (T183+T183+T221)
Dilution rate
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/50 FC: 1/50-1/100
Stockpile
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Other name
JNK 46; JNK 55; MAPK10; MAPK9; MAPK8; SAPK1b; SAPK1; SAPK; PRKM10; PRKM9; PRKM8
Background
Serine/threonine-protein kinase involved in various processes such as cell proliferation, differentiation, migration, transformation and programmed cell death. Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway.
