Reactive species
Human,Rat,Mouse
Antibody type
Monoclonal antibodies
Dalton（DA）
Calculated MW: 50 kDa; Observed MW: 50 kDa
Immunogen
Purified recombinant protein expressed in E.coli.
Dilution rate
WB: 1/500-1/1000 IHC: 1/50-1/100
Stockpile
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Other name
FAAR; NR1C2; NUC1; Peroxisome proliferative activated receptor delta
Background
Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand.
