Reactive species
Human,Mouse,Rat
Antibody type
Monoclonal antibodies
Dalton(DA)
Calculated MW: 36 kDa; Observed MW: 28 kDa
Immunogen
synthesized peptide derived from human NEK6
Dilution rate
WB: 1/500-1/1000 IP: 1/50
Stockpile
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Other name
NEK6; NimA related protein kinase 6; SID61512
Background
Activated during M phase. Required for chromosome segregation at metaphase-anaphase transition and therefore for mitotic progression. Inhibition of activity results in apoptosis. Phosphorylates KIF11 to promote mitotic spindle formation.