Reactive species
Human,Mouse
Applications
WB,IHC-P,FC,ELISA
Antibody type
Monoclonal antibodies
Dalton（DA）
Calculated MW: 60 kDa;Observed MW: 60 kDa
Immunogen
Purified recombinant fragment of human SLC22A12 expressed in E. Coli.
Dilution rate
WB: 1/500-1/1000 IHC: 1/100-1/200 FC: 1/50-1/100 ELISA: 1/10000
Stockpile
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Other name
RST; OAT4L; URAT1
Background
The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants.
