Reactive species
Human,Mouse,Rat
Applications
WB,IHC-P,ICC/IF,IP
Antibody type
Monoclonal antibodies
Dalton(DA)
Calculated MW: 79 kDa;Observed MW:50-70kDa
Immunogen
synthesized peptide derived from human Phospho-Tau (S404)
Dilution rate
WB: 1/500-1/1000 IHC: 1/100-1/200 IF: 1/50-1/200 IP: 1/50
Stockpile
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Other name
MAPT; Microtubule-associated protein tau; MTBT1; Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau
Background
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both.