Antibody type
Monoclonal antibodies
Dalton(DA)
Calculated MW: 58 kDa;Observed MW:57kDa
Immunogen
synthesized peptide derived from human PPAR gamma
Dilution rate
WB: 1/500-1/1000
Stockpile
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Other name
CIMT1; GLM1; NR1C3; PPAR gamma; PARG; PPARG1; PPARG2;
Background
Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis.