Reactive species
Human,Mouse,Rat
Applications
WB,IHC-P,ICC/IF,IP,ChIP
Antibody type
Polyclonal Antibody
Dalton（DA）
Calculated MW: 15 kDa; Observed MW: 15 kDa
Immunogen
A synthetic acetylated peptide corresponding to residues surrounding K18 of human H3
Dilution rate
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/50-1/200 ChIP: 1:20 - 1:100
Stockpile
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Other name
H3K18ac; H3/j; H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3FJ; H3C10; H3C11; HIST1H3J
Background
H3 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.
