Reactive species
Human,Mouse,Rat
Antibody type
Monoclonal antibodies
Dalton(DA)
Calculated MW: 84 kDa; Observed MW: 84 kDa
Immunogen
synthesized peptide derived from human CD168
Dilution rate
WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/50
Stockpile
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Other name
HMMR; IHABP; RHAMM; Hyaluronan mediated motility receptor; Intracellular hyaluronic acid-binding protein; Receptor for hyaluronan-mediated motility; CD antigen CD168
Background
Involved in cell motility. When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity.