Reactive species
Human,Mouse,Rat,Hamster
Antibody type
Monoclonal antibodies
Dalton(DA)
Calculated MW: 85 kDa; Observed MW: 85 kDa
Immunogen
synthetic peptide of human beta Catenin
Dilution rate
WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
Stockpile
Store at 4°C short term. Aliquotand store at -20°C long term. Avoid freeze/thaw cycles.
Other name
CTNNB1; CTNNB; OK/SW-cl.35; Catenin beta-1; Beta-catenin
Background
Beta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior.