Reactive species
Human,Mouse,Rat
Applications
WB,IHC-F,IHC-P,ICC/IF,IP
Antibody type
Monoclonal antibodies
Gene Name
HSP90AA1/HSP90AB1
Dalton(DA)
Calculated MW: 85 kDa; Observed MW: 90 kDa
Immunogen
Recombinant protein of human Hsp90 beta
Dilution rate
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Stockpile
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Background
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation.